Year: 2018
Type: article
Abstract: Flowering time (heading date) in rice (Oryza sativa) is an important agronomic trait that determines yield. The levels of histone H3 lysine 4 trimethylation (H3K4me3) modulated by TRITHORAX-like proteins regulate gene transcription, flowering time and environmental stress responses. However, plant TRITHORAX-like proteins have no known DNA-binding domain, and therefore the mechanism that gives sequence specificity to these proteins remains unclear. Here, we show that the rice TRITHORAX-like protein OsTrx1 is recruited to its target, Early heading date 1 (Ehd1), by the C2H2 zinc finger protein SDG723/OsTrx1/OsSET33 Interaction Protein 1 (SIP1). SIP1 binds to the promoter of Ehd1 and interacts with OsTrx1. Mutations in SIP1 led to a late heading date under long-day and short-day conditions. Defects in OsTrx1 or SIP1 led to reduced H3K4me3 levels at Ehd1, thus reducing Ehd1 expression. Together, our results show that the transcription factor SIP1 interacts with OxTrx1, allowing OsTrx1 to specifically target Ehd1, altering H3K4me3 levels, increasing Ehd1 expression and thereby promoting flowering.
Source: New Phytologist
DOI: 10.1111/nph.15122
Authors: Pengfei Jiang, Shiliang Wang, Han Zheng, Hao Li, Fei Zhang, Yanhua Su, Zuntao Xu, Haiyan Lin, Qian Qian, Yong Ding
Institutions: University of Science and Technology of China, Anhui Agricultural University, Chinese Academy of Sciences, Center for Excellence in Molecular Plant Sciences, Anhui Academy of Agricultural Sciences, Chinese Academy of Agricultural Sciences, China National Rice Research Institute, State Key Laboratory of Rice Biology
Language: English
Subfield: Plant Science
Domain: Life Sciences
SDG: Zero hunger
Open Access status: hybrid
Estimated APC paid: $5,790
Awards: G1687627230, G5234600281, G946538050
OpenAlex ID: W2796393590