Year: 2018
Type: article
Abstract: The sulfoximine derivatives are widely known for their potent biological and medicinal activities.Recently, due to the transition-metal catalysis, great advancements have been achieved in the synthesis of sulfoximine derivatives.Utilizing free NH-sulfoximines as the starting materials, various the direct N-H functionalizations can be accomplished, such as alkynylation, alkenylation, alkylation, arylation, etc.In addition, the ortho arene C(sp 2 )-H activation can also be obtained through C-H activation reaction with the assistance of S＝NH as intramolecular directing groups, thus giving varies (hetero)aromatic molecules.N-H and C-H functionalization reactions of sulfoximines were summarized, and the mechanisms of some novel model reactions are also briefly discussed.Keywords NH-sulfoximine; transition-
Authors: Hao Zhou, Zhiyuan Chen
Institution: Jiangxi Normal University
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: bronze
OpenAlex ID: W2796897378