Year: 2018
Type: review
Abstract: Traditional supplements of selenium generally have a low degree of absorption and increased toxicity. Therefore, it is imperative to develop innovative systems as transporters of selenium compounds, which would raise the bioavailability of this element and allow its controlled release in the organism. Nanoscale selenium has attracted a great interest as a food additive especially in individuals with selenium deficiency, but also as a therapeutic agent without significant side effects in medicine. This review is focused on the incorporation of nanotechnological applications, in particular exploring the possibilities of a more effective way of administration, especially in selenium-deficient organisms. In addition, this review summarizes the survey of knowledge on selenium nanoparticles, their biological effects in the organism, advantages, absorption mechanisms, and nanotechnological applications for peroral administration.
DOI: 10.2147/ijn.s157541
Institutions: Mendel University in Brno, Wroclaw Medical University, University of Veterinary Sciences Brno, Robert Gordon University, Yanshan University, State Key Laboratory of Metastable Materials Science and Technology, University of Chemistry and Technology, Prague, Council for Nutritional and Environmental Medicine
Language: English
Subfield: Nutrition and Dietetics
Field: Nursing
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,836
OpenAlex ID: W2796973106