Work

Synthesis and structure-activity relationship of furoquinolinediones as inhibitors of Tyrosyl-DNA phosphodiesterase 2 (TDP2)

Year: 2018

Type: article

Source: European Journal of Medicinal Chemistry

DOI: 10.1016/j.ejmech.2018.04.024

Authors: Le-Mao Yu, Zhu Hu, Yu Chen, Azhar Ravji, Sophia Lopez, Caroline B. Plescia, Qian Yu, Hui Yang, Monica Abdelmalak, Sourav Saha, Keli Agama, Evgeny Kiselev, Christophe Marchand, Yves Pommier, Lin-Kun An

Institutions: Sun Yat-sen University, National Institutes of Health, National Cancer Institute, Center for Cancer Research

Language: English

Topic: Cancer therapeutics and mechanisms

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Natural Science Foundation of China, Natural Science Foundation of Guangdong Province, National Institutes of Health, National Cancer Institute

Awards: DNA Topoisomerases as Target of Action of Anticancer Drugs, G4962365099, 新机制的Azan类拓扑异构酶I抑制剂的设计、合成及抗肿瘤研究, G9000020722, G9000173957, G998031209

OpenAlex ID: W2796997342

FWCI: 0.863

Cites: 43

Cited by: 19

Related to: 10