The National Institute on Aging and the Alzheimer's Association Research Framework for Alzheimer's disease: Perspectives from the Research Roundtable
Year: 2018
Type: article
Abstract: The Alzheimer's Association's Research Roundtable met in November 2017 to explore the new National Institute on Aging and the Alzheimer's Association Research Framework for Alzheimer's disease. The meeting allowed experts in the field from academia, industry, and government to provide perspectives on the new National Institute on Aging and the Alzheimer's Association Research Framework. This review will summarize the "A, T, N System" (Amyloid, Tau, and Neurodegeneration) using biomarkers and how this may be applied to clinical research and drug development. In addition, challenges and barriers to the potential adoption of this new framework will be discussed. Finally, future directions for research will be proposed.
Source: Alzheimer s & Dementia
Authors: David S. Knopman, Samantha Budd Haeberlein, Maria C. Carrillo, James A. Hendrix, Geoff Kerchner, Richard Margolin, Paul Maruff, David S. Miller, Gary Tong, Maria B. Tome, Melissa E. Murray, Peter T. Nelson, Mary Sano, Niklas Mattsson, David L. Sultzer, Thomas J. Montine, Clifford R. Jack, Hartmuth Kolb, Ronald C. Petersen, Prashanthi Vemuri, Megan Zoschg Canniere, Julie A. Schneider, Susan M. Resnick, Gary Romano, Argonde Corien van Harten, David A. Wolk, Lisa J. Bain, Eric Siemers
Institutions: Mayo Clinic, Biogen (United States), Alzheimer's Association, Genentech, Pfizer (United States), Lundbeck (United States), European Medicines Agency, Mayo Clinic in Florida, University of Kentucky, Icahn School of Medicine at Mount Sinai, Lund University, University of California, Los Angeles, Stanford Medicine, Stanford University, Roche (Switzerland), Rush University Medical Center, National Institute on Aging, Amsterdam UMC Location Vrije Universiteit Amsterdam, University of Pennsylvania, Eli Lilly (United States)
Language: English
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: green
Awards: G228323703, G384347443, G7423759087
OpenAlex ID: W2797129551