Work

Enhanced Bacterial Immunity and Mammalian Genome Editing via RNA-Polymerase-Mediated Dislodging of Cas9 from Double-Strand DNA Breaks

Year: 2018

Type: article

Source: Molecular Cell

DOI: 10.1016/j.molcel.2018.06.005

Authors: Ryan Clarke, Robert Heler, Matthew S. MacDougall, Nan Cher Yeo, Alejandro Chavez, Maureen Regan, Leslyn Hanakahi, George M. Church, Luciano A. Marraffini, Bradley J. Merrill

Institutions: University of Illinois Chicago, Rockefeller University, Harvard University, Wyss Institute for Biologically Inspired Engineering, University of Illinois Chicago, Rockford campus

Language: English

Topic: CRISPR and Genetic Engineering

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

Funders: Howard Hughes Medical Institute, Burroughs Wellcome Fund, National Institutes of Health, Center for Clinical and Translational Sciences, University of Texas Health Science Center at Houston, Hansjörg Wyss Institute for Biologically Inspired Engineering, Harvard University, National Human Genome Research Institute, National Institute of Allergy and Infectious Diseases, National Center for Advancing Translational Sciences, Eunice Kennedy Shriver National Institute of Child Health and Human Development

Awards: G1816012062, G2343407422, G3986563173, Using CRISPR immunity to prevent the spread of virulence traits among pathogens, G797306165, Wnt/Beta-catenin and Tcf/Lef factor regulation of pluripotency, G9000109222, G9000169037

OpenAlex ID: W2797604131

FWCI: 6.445

Cites: 43

Cited by: 143

Related to: 10