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Nanoparticles Conjugated with Photocleavable Linkers for the Intracellular Delivery of Biomolecules

Year: 2018
Type: article
Abstract: We report the synthesis and characterization of phototriggerable polymeric nanoparticles (NPs) for the intracellular delivery of small molecules and proteins to modulate cell activity. For that purpose, several photocleavable linkers have been prepared providing diverse functional groups as anchoring points for biomolecules.
DOI: 10.1021/acs.bioconjchem.7b00820
Authors: Adrián Jiménez-Balsa, Sandra Pinto, Emanuel Quartin, Miguel M. Lino, Vitor Francisco, Lino Ferreira
Language: English
Subfield: Biomaterials
Open Access status: green
Funders: European Commission, Universidade de Coimbra, Consellería de Cultura, Educación e Ordenación Universitaria, Xunta de Galicia, Fundação para a Ciência e a Tecnologia, European Regional Development Fund, FP7 Ideas: European Research Council
Awards: Triggerable nanomaterials to modulate cell activity, G4862999893, Development of biocompatible light-activable nanocarriers to improve hematopoietic stem cell engraftment, MODULATION OF HEMATOPOIETIC STEM CELL (HSC) ACTIVITY BY LIGHT-TRIGGERABLE NANOPARTICLES, Enhancing Research in Ageing at the University of Coimbra, Triggerable nanomaterials to modulate cell activity
OpenAlex ID: W2797759296
FWCI: 0.598
Cites: 29
Cited by: 14
Related to: 10