Learning to live with Mild Cognitive Impairment. Development and evaluation of a psychological intervention for patients with Mild Cognitive Impairment, and their significant others.
Year: 2012
Type: dissertation
Abstract: Conversion to dementiaOriginally, each MCI subtype was related to a presumed aetiology.These presumed aetiologies and the conversion rates to dementia have been subject of many epidemiological studies on MCI.Ten years after Petersen's description of MCI, progress on clinical, epidemiological disease mechanisms and intervention trials were summarized.It was found that annual progression to dementia varies from 6% to 10% in a general population and from 10% to 15% in memory clinic populations.These rates are seriously elevated compared to the base incidence rates of dementia of 1% to 2% per year.Factors related to an increased rate of progression include age, delayed-recall performance on memory tests, atrophy on MRI and CSF markers compatible with Alzheimer's disease (Petersen, 2009).A recent study showed that below-average performance on several cognitive domains, including the memory domain, is associated with an increased risk to develop Alzheimer's dementia (Visser, 2009).Although the risk to develop dementia is heightened, a substantial group of MCI patients remains stable over longer periods of time (sometimes even up to several years), and a third small group will even revert to age-normal levels of cognitive functioning.MCI patients can 'recover' when aetiologies such as a depression or cardiovascular disease underlie the symptoms.In summary, MCI reflects a very heterogeneous group of patients with different courses and causes. 1 appraisals for the experienced distress in persons with MCI.It was found that the meaning participants attributed to their diagnosis widely varied depending on their expectations with respect to normal aging, personal experience with dementia, and concurrent health problems.For example, an individual who viewed memory 1
Author: Etienne Joosten
Language: English
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funders: Radboud Universiteit, Alzheimer Nederland
OpenAlex ID: W2798250969