Work

Genetic background of early life telomere length and association with dairy cow longevity

Year: 2018

Type: conference-paper

Abstract: Involuntary culling is a major cause of economic loss in dairy cows. Here we examine the genetic background of telomere length (TL) and its association with dairy cow longevity, using the largest dataset of TL measurement in livestock species. Heritability of TL at birth (TLB) was moderate and significant. A genome-wide association study (GWAS) revealed three suggestive genome-wide significant SNPs on chromosomes 1 and 23 affecting TLB. Significant phenotypic correlations of TLB with a range of longevity traits and a significant genetic correlation with survival to 48 months of age were also estimated. Keywords: longevity, dairy, telomere length, biomarker, GWAS

Source: Edinburgh Research Explorer (University of Edinburgh)

Authors: Joanna J. Ilska, Androniki Psifidi, Luise A. Seeker, Bruce Whitelaw, M.P. Coffey, Daniel H. Nussey, Georgios Banos

Institutions: University of Edinburgh, Scotland's Rural College

Language: English

Topic: Genetic and phenotypic traits in livestock

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Zero hunger

Open Access status: green

OpenAlex ID: W2799948711

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