Work

Smart gold nanoparticle-stabilized ultrasound microbubbles as cancer theranostics

Year: 2018

Type: article

Abstract: Smart gold nanoparticle-stabilized microbubbles (SAuMBs) composed of a gas-filled core and shell including smart gold nanoparticles (SAuNPs) which can be aggregated in tumors were applied as ultrasound-mediated cancer theranostics. The gas core in the microstructure enabled the detection of tumors using ultrasound and facilitated the delivery of SAuNPs by sonoporation. The SAuNPs spontaneously aggregated in tumors, which allowed photoacoustic (PA) monitoring and photothermal treatment (PTT) of tumors.

Source: Journal of Materials Chemistry B

DOI: 10.1039/c8tb00368h

Authors: Young Il Yoon, Xin Pang, Sungwook Jung, Guofeng Zhang, Minsuk Kong, Gang Liu, Xiaoyuan Chen

Institutions: National Institutes of Health, National Institute of Biomedical Imaging and Bioengineering, Korea Textile Development Institute, Xiamen University, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Cancer Institute

Language: English

Topic: Nanoplatforms for cancer theranostics

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Natural Science Foundation of China, Korea Research Institute of Bioscience and Biotechnology, University of Chinese Academy of Sciences, National Institutes of Health, National Institute of Biomedical Imaging and Bioengineering

Awards: G1199124822, Laboratory of Molecular Imaging and Nanomedicine, G2754838152, G4307406393, G6972888113, G7995306448, G8502738828, G92131997

OpenAlex ID: W2800075519

FWCI: 1.199

Cites: 22

Cited by: 29

Related to: 10