Work

[FeFe]-Hydrogenases: recent developments and future perspectives

Year: 2018

Type: article

Abstract: [FeFe]-Hydrogenases are the most efficient enzymes for catalytic hydrogen turnover. Their H2 production efficiency is hitherto unrivalled. However, functional details of the catalytic machinery and possible modes of application are discussed controversially. The incorporation of synthetically modified cofactors and utilization of semi-artificial enzymes only recently allowed us to shed light on key steps of the catalytic cycle. Herein, we summarize the essential findings regarding the redox chemistry of [FeFe]-hydrogenases and discuss their catalytic hydrogen turnover. We furthermore will give an outlook on potential research activities and exploit the utilization of synthetic cofactor mimics.

Source: Chemical Communications

DOI: 10.1039/c8cc01275j

Authors: F. Wittkamp, M. Senger, S. T. Stripp, U.-P. Apfel

Institutions: Ruhr University Bochum, Freie Universität Berlin, Fraunhofer Institute for Environmental, Safety and Energy Technology UMSICHT

Language: English

Topic: Metalloenzymes and iron-sulfur proteins

Subfield: Renewable Energy, Sustainability and the Environment

Field: Energy

Domain: Physical Sciences

Open Access status: bronze

Funders: Deutsche Forschungsgemeinschaft, Studienstiftung des Deutschen Volkes, International Max Planck Research School for Advanced Methods in Process and Systems Engineering

Award: G4511000172