Work

Dichlorophenyl piperazines, including a recently-approved atypical antipsychotic, are potent inhibitors of DHCR7, the last enzyme in cholesterol biosynthesis

Year: 2018

Type: article

Source: Toxicology and Applied Pharmacology

DOI: 10.1016/j.taap.2018.04.029

Authors: Thiago C. Genaro-Mattos, Keri A. Tallman, Luke B. Allen, Allison Anderson, Karoly Mirnics, Zeljka Korade, Ned A. Porter

Institutions: Vanderbilt University, University of Nebraska Medical Center

Language: English

Topic: Cholesterol and Lipid Metabolism

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Foundation for the National Institutes of Health, National Institutes of Health, National Institute of Mental Health, National Institute of Environmental Health Sciences, Eunice Kennedy Shriver National Institute of Child Health and Human Development

Awards: SLOS and Neuronal Oxidative Stress, G1922789812, G2813732898, G3403902456, G3792226487, Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at Vanderbilt University, G7042895464, Vulnerability of DHCR7+/- mutation carriers to aripiprazole and trazodone treatment, Ozone, oxysterols, and lung inflammation, G9000053986, G9000313313

OpenAlex ID: W2803093375

FWCI: 4.71

Cites: 47

Cited by: 42

Related to: 10