Viral infections and bronchial asthma
Year: 2018
Type: article
Abstract: Respiratory viruses represent an important trigger of asthma exacerbations, in both adults and children. Upper respiratory viral infections are responsible for 80% of asthma exacerbation in children and for 50% of acute episodes in adults. The interactions between the virulence of viruses, genetic factors and environmental exposure (airway microbiome) could determine more severe respiratory illness, which increase the risk of progression to asthma. The most frequently noticed respiratory infections involved in asthma exacerbations or in its inception are human rhinoviruses and respiratory syncytial viruses. The association of a specific viral infection with asthma exacerbation is variable among different geographic areas, according to the age and the type of studied population. Recent studies have proven an inverse association between allergic respiratory disease and viral infections: the presence of allergic inflammation may favor the occurrence of specific viral infections.
Source: Alergologia
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W2803507631
