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Trametinib in Histiocytic Sarcoma with an Activating MAP2K1 (MEK1) Mutation

Year: 2018

Type: article

Abstract: Trametinib in Histiocytic Sarcoma In a patient with treatment-refractory follicular lymphoma, a biopsy showed a histiocytic sarcoma related to the lymphoma but with an activating mutation in MAPK2....

Source: New England Journal of Medicine

DOI: 10.1056/nejmc1511490

Authors: Mrinal M. Gounder, David B. Solit, William D. Tap

Institution: Memorial Sloan Kettering Cancer Center

Language: English

Topic: Histiocytic Disorders and Treatments

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Memorial Sloan-Kettering Cancer Center, National Cancer Institute

Awards: G289723095, Cancer Center Support Grant

OpenAlex ID: W2803287631

FWCI: 4.597

Cites: 5

Cited by: 78

Related to: 10