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Endothelin A Receptor Antagonist Alleviates Allodynia in a Rat Model of Complex Regional Pain Syndrome

Year: 2017
Type: article
Abstract: The traditional pharmacologic therapies for Complex Regional Pain Syndrome (CRPS) remain ineffective. Endothelin A (ET-A) receptor contributes significantly to the development and maintenance of pain in CRPS, and presents a target for novel therapies. We assessed the effects of the ET-A receptor antagonist BQ-123 on nociceptive sensitization, in a rat model of Chronic Post-Ischemia Pain (CPIP).
DOI: 10.31480/2330-4871/059
Authors: Qing Miao, Kong Er-liang, Zhang Yan, Di Hui-ting, Sun Yu-ming, Zhang Jin-min, Yu Wei-feng, Wu Fei-xiang
Institutions: Second Military Medical University, Eastern Hepatobiliary Surgery Hospital, Wenzhou Medical University, Zhoushan Hospital, Rutgers, The State University of New Jersey, Rutgers New Jersey Medical School
Language: English
Field: Medicine
Open Access status: diamond
Award: G957976507
OpenAlex ID: W2803460005
FWCI:
Cites: 17
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Related to: 10