Work

MMP1/PAR1/SP/NK1R paracrine loop modulates early perineural invasion of pancreatic cancer cells

Year: 2018

Type: article

Abstract: In this study, we provided evidence that the MMP1/PAR1/SP/NK1R paracrine loop contributes to PNI during the early stage of primary tumor formation. Furthermore, we established a sensitive and non-invasive method to detect nerve invasion using iron oxide nanoparticles and MRI.

Source: Theranostics

DOI: 10.7150/thno.24281

Authors: Chumei Huang, Yaqing Li, Yubo Guo, Zuoquan Zhang, Guoda Lian, Yinting Chen, Jian Li, Yonghui Su, Jiajia Li, Kege Yang, Shaojie Chen, Hong Su, Kaihong Huang, Linjuan Zeng

Institutions: Sun Yat-sen University, The Seventh Affiliated Hospital of Sun Yat-sen University, Sun Yat-sen Memorial Hospital, Jinan University, Zhuhai People's Hospital, Fifth Affiliated Hospital of Sun Yat-sen University

Language: English

Topic: Cancer, Stress, Anesthesia, and Immune Response

Subfield: Psychiatry and Mental health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,671

OpenAlex ID: W2803542974

FWCI: 8.594

Cites: 50

Cited by: 102

Related to: 10