Work

Integrative analysis of gut microbiota composition, host colonic gene expression and intraluminal metabolites in aging C57BL/6J mice

Year: 2018

Type: article

Abstract: spp. This study demonstrates that aging is associated with pronounced changes in gut microbiota composition and colonic gene expression. Furthermore, the strong correlations between specific bacterial genera and host gene expression may imply that orchestrated interactions take place in the vicinity of the colonic wall and potentially mediate colonic health during aging.

Source: Aging

DOI: 10.18632/aging.101439

Authors: Benthe van der Lugt, Fenni Rusli, Carolien Lute, Andreas Lamprakis, Ethel Salazar, Mark V. Boekschoten, Guido J. Hooiveld, Michael Müller, Jacques Vervoort, Sander Kersten, Clara Belzer, Dieuwertje E.G. Kok, Wilma T. Steegenga

Institutions: Wageningen University & Research, University of East Anglia

Language: English

Topic: Gut microbiota and health

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: European Commission, Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Awards: G2476663878, G5702163051, Graduate Programme on Food Structure, Digestion and Health, Integrated research on DEvelopmental determinants of Aging and Longevity

OpenAlex ID: W2804002517

FWCI: 3.015

Cites: 64

Cited by: 72

Related to: 10