Work

The fission yeast Stn1-Ten1 complex limits telomerase activity via its SUMO-interacting motif and promotes telomeres replication

Year: 2018

Type: article

Abstract: mutant. Together, our results show that the Stn1-Ten1 complex has a dual function at telomeres by limiting telomerase action and promoting chromosome end replication.

Source: Science Advances

DOI: 10.1126/sciadv.aar2740

Authors: Samah Matmati, Mélina Vaurs, José M. Escandell, Laetitia Maestroni, Toru M. Nakamura, Miguel G. Ferreira, Vincent Géli, Stéphane Coulon

Institutions: Centre National de la Recherche Scientifique, Inserm, Aix-Marseille Université, Centre de Recherche en Cancérologie de Marseille, Institut Paoli-Calmettes, Instituto Gulbenkian de Ciência, University of Illinois Chicago, KDDI Research (Japan), Institut de Recherche sur le Cancer et le Vieillissement de Nice, Université Nice Sophia Antipolis

Language: English

Topic: Telomeres, Telomerase, and Senescence

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

Open Access status: gold

Estimated APC paid: $3,224

Funders: Agence Nationale de la Recherche, National Institutes of Health, National Institute of General Medical Sciences

Awards: G2536237639, Regulation of Telomere Maintenance in Fission Yeast

OpenAlex ID: W2804483413

FWCI: 2.39

Cites: 58

Cited by: 33

Related to: 10