When change is the only constant: The promise of longitudinal neuroimaging in understanding social anxiety disorder
Year: 2018
Type: review
Abstract: Longitudinal studies offer a unique window into developmental change. Yet, most of what we know about the pathophysiology of psychiatric disorders is based on cross-sectional work. Here, we highlight the importance of adopting a longitudinal approach in order to make progress towards identifying the neurobiological mechanisms of social anxiety disorder (SAD). Using examples, we illustrate how longitudinal data can uniquely inform SAD etiology and timing of interventions. The brain's inherently adaptive quality requires that we model risk correlates of disorders as dynamic in their expression. Developmental theories regarding timing of environmental events, cascading effects and (mal)adaptations of the developing brain will be crucial components of comprehensive, integrative models of SAD. We close by discussing analytical considerations when working with longitudinal, developmental data.
Language: English
Subfield: Experimental and Cognitive Psychology
Field: Psychology
Domain: Social Sciences
Open Access status: gold
Estimated APC paid: $3,650
Funders: King’s College London, South London and Maudsley NHS Foundation Trust, National Institute for Health and Care Research, King's College London, National Institutes of Health, Medical Research Council, European Research Council, National Institute of Mental Health, FP7 Ideas: European Research Council
OpenAlex ID: W2804672064
