Work

Effect of childhood socioeconomic conditions on cancer onset in later life: an ambidirectional cohort study

Year: 2018

Type: article

Study design: Observational Study

Abstract: OBJECTIVES: Living in low socioeconomic conditions during childhood is associated with poor health outcomes in later life. Whether this link also applies to cancer is unclear. We examined whether childhood socioeconomic conditions (CSCs) are associated with cancer risk in later life and whether this effect remained after adjusting for adulthood socioeconomic conditions (ASCs). METHODS: Data for 26,431 individuals ≥ 50 years old included in SHARE were analysed. CSCs were constructed by using indicators of living conditions at age 10. ASC indicators were education, main occupation, and household income. Gender-stratified associations of CSCs with cancer onset (overall and by site) were assessed by Cox regression. RESULTS: In total, 2852 individuals were diagnosed with cancer. For both men and women, risk of overall cancer was increased for advantaged CSCs and remained so after adjusting for ASCs (hazard ratio = 1.36, 95% CI 1.10, 1.63, and 1.70, 95% CI 1.41, 2.07). CONCLUSIONS: Advantaged CSCs are associated with an increased risk of overall cancer at older age, but results vary by cancer sites and sex. Participation in cancer screening or exposure to risk factors may differ by social conditions.

Source: International Journal of Public Health

DOI: 10.1007/s00038-018-1111-9

Authors: Bernadette W. A. van der Linden, Delphine S. Courvoisier, Boris Cheval, Stefan Sieber, Piet Bracke, Idris Guessous, Claudine Burton-Jeangros, Matthias Kliegel, Stéphane Cullati

Institutions: University of Geneva, Ghent University, Emory University, Centre Hospitalier Universitaire Vaudois, University Hospital of Geneva, Institute of Social and Preventive Medicine, University of Lausanne

Language: English

Topic: Health disparities and outcomes

Subfield: Health

Field: Social Sciences

Domain: Social Sciences

SDGs: Good health and well-being, Reduced inequalities

Open Access status: hybrid

Estimated APC paid: $2,775

Funders: National Science Foundation, European Commission, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, Max-Planck-Gesellschaft, National Institutes of Health, Horizon 2020, National Institute on Aging

Awards: Multinational Advancement of Research Infrastructures on Ageing, G1178032220, G1237079599, G1319460257, G1330667123, G1428006373, G1608581485, G1708035608, G1750703574, G1778268290, Methodologies and Data mining techniques for the analysis of Big Data based on Longitudinal Population and Epidemiological Registers, G1820526844, G2077389594, G2343781458, G2465118858, G2496819784, G2573814836, G3166864496, G3188738659, G323020161, G3457581384, G3687180791, G4165969582, RAND Center for the Study of Aging, G434337789, Upgrading the Survey of Health, Ageing and Retirement in Europe – preparatory phase, G4545110052, G4569152855, G4723430573, G4847675667, G503278667, G504669776, G5207492846, G5618942462, G5849176554, G5857780965, G598697797, G6053673296, G6055688980, G6476390097, G6678519423, G6969501727, NCCR LIVES: Overcoming vulnerability - life course perspectives, G8072554765, Longitudinal Enhancement and Access imProvement of the SHARE infrastructure, G8875743412, Health and Retirement Study: Yrs 35-40, G938892667, G939349750

OpenAlex ID: W2804781075

FWCI: 6.4

Cites: 39

Cited by: 32

Related to: 10