Work

Potential-Controlled Adsorption, Separation, and Detection of Redox Species in Nanofluidic Devices

Year: 2018

Type: article

Abstract: Nanoscale channels and electrodes for electrochemical measurements exhibit extreme surface-to-volume ratios and a correspondingly high sensitivity to even weak degrees of surface interactions. Here, we exploit the potential-dependent reversible adsorption of outer-sphere redox species to modulate in space and time their concentration in a nanochannel under advective flow conditions. Induced concentration variations propagate downstream at a species-dependent velocity. This allows one to amperometrically distinguish between attomole amounts of species based on their time-of-flight. On-demand concentration pulse generation, separation, and detection are all integrated in a miniaturized platform.

Source: Analytical Chemistry

DOI: 10.1021/acs.analchem.8b01719

Authors: Jin Cui, Klaus Mathwig, Dileep Mampallil, Serge G. Lemay

Institution: University of Twente

Language: English

Topic: Electrochemical Analysis and Applications

Subfield: Electrochemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $4,500

Funders: Nederlandse Organisatie voor Wetenschappelijk Onderzoek, FP7 Ideas: European Research Council