Work

Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction

Year: 2018

Type: article

Source: Nature Biotechnology

DOI: 10.1038/nbt.4172

Authors: Luke W Koblan, Jordan L Doman, Christopher Wilson, Jonathan M Levy, Tristan Tay, Gregory A Newby, Juan Pablo Maianti, Aditya Raguram, David R Liu

Institutions: Broad Institute, Howard Hughes Medical Institute, Harvard University, Massachusetts Institute of Technology

Language: English

Topic: CRISPR and Genetic Engineering

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: Howard Hughes Medical Institute, National Human Genome Research Institute, National Cancer Institute, National Institute of General Medical Sciences, National Institute of Biomedical Imaging and Bioengineering

Awards: G1001736056, G5052434461, G7486275663, Continuous Evolution of Proteins with Novel Therapeutic Potential, Cancer Center Support (Core) Grant

OpenAlex ID: W2805505209

FWCI: 24.87

Cites: 35

Cited by: 940

Related to: 10