Work

Inflammation and Neuro-Immune Dysregulations in Autism Spectrum Disorders

Year: 2018

Type: review

Abstract: Autism Spectrum Disorder (ASD) is characterized by persistent deficits in social communication and interaction and restricted-repetitive patterns of behavior, interests, or activities. Strong inflammation states are associated with ASD. This inflammatory condition is often linked to immune system dysfunction. Several cell types are enrolled to trigger and sustain these processes. Neuro-inflammation and neuro-immune abnormalities have now been established in ASD as key factors in its development and maintenance. In this review, we will explore inflammatory conditions, dysfunctions in neuro-immune cross-talk, and immune system treatments in ASD management.

Source: Pharmaceuticals

DOI: 10.3390/ph11020056

Authors: Dario Siniscalco, Stephen Schultz, Anna Lisa Brigida, Nicola Antonucci

Institutions: University of Campania "Luigi Vanvitelli", La Forza del Silenzio, The University of Texas at San Antonio Health Science Center

Language: English

Topic: Autism Spectrum Disorder Research

Subfield: Cognitive Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,499