Work

Understanding and overcoming trade-offs between antibody affinity, specificity, stability and solubility

Year: 2018

Type: article

Source: Biochemical Engineering Journal

DOI: 10.1016/j.bej.2018.06.003

Authors: Lilia A. Rabia, Alec A. Desai, Harkamal S. Jhajj, Peter M. Tessier

Institutions: Rensselaer Polytechnic Institute, University of Michigan

Language: English

Topic: Monoclonal and Polyclonal Antibodies Research

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

Open Access status: bronze

Funders: National Science Foundation, National Institutes of Health, National Institute of General Medical Sciences

Awards: Design of conformation-specific antibodies against unfolded and misfolded proteins, G2443809039, GOALI: Methods for designing antibodies specific for intrinsically disordered proteins, G9000021190

OpenAlex ID: W2805822355

FWCI: 6.76

Cites: 84

Cited by: 157

Related to: 10