Work

Pre‐Metastatic Niche: Biomaterial Scaffolds as Pre‐metastatic Niche Mimics Systemically Alter the Primary Tumor and Tumor Microenvironment (Adv. Healthcare Mater. 10/2018)

Year: 2018

Type: article

Abstract: Biomaterial implants that mimic the premetastatic niche are shown to redirect immune and tumor cell populations in vivo. However, the systemic effects of premetastatic niche mimics on metastasis progression have yet to be characterized. In article 1700903 by Lonnie D. Shea and co-workers, synthetic biomaterial implants are shown to systemically alter the primary tumor and the tumor microenvironment to promote an invasion-suppressive phenotype. Cover art designed and produced by Stephen Alvey, University of Michigan, Department of Engineering.

Source: Advanced Healthcare Materials

DOI: 10.1002/adhm.201870040

Authors: Brian A. Aguado, Rachel M. Hartfield, Grace G. Bushnell, Joseph T. Decker, Samira M. Azarin, Dhaval Nanavati, Matthew J. Schipma, Shreyas S. Rao, Robert S. Oakes, Yining Zhang, Jacqueline S. Jeruss, Lonnie D. Shea

Institutions: Northwestern University, University of Michigan, University of Minnesota, University of Minnesota System, University of Alabama

Language: English

Topic: Cancer Cells and Metastasis

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W2805834233

FWCI:

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