Work

Pulling the genome in opposite directions to dissect gene networks

Year: 2018

Type: article

Abstract: Orthogonal CRISPR-Cas systems have been integrated into combinatorial screens to decipher complex genetic relationships in two recent studies.

Source: Genome biology

DOI: 10.1186/s13059-018-1425-1

Authors: Charles A. Gersbach, Rodolphe Barrangou

Institutions: Duke University, Duke Medical Center, North Carolina State University

Language: English

Topic: CRISPR and Genetic Engineering

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $5,490

Funders: Foundation for the National Institutes of Health, North Carolina State University, North Carolina Agricultural Foundation, Paul G. Allen Frontiers Group, National Institute on Drug Abuse, National Human Genome Research Institute

Awards: G1482182431, G2622399766, In Vivo Epigenome Editing with CRISPR-Based Histone Acetyltransferase Transgenic Mice, Decoding and Reprogramming the Corticosteroid Transcriptional Regulatory Network, G3801236473, Engineering Targeted Epigenetic Modifiers for Precise Control of Gene Regulation, Regulatory Mechanisms of CD4+ T Cell Differentiation, G8506126476

OpenAlex ID: W2806142780

FWCI: 0.178

Cites: 10

Cited by: 2

Related to: 10