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Cellular microRNA detection with miRacles: microRNA- activated conditional looping of engineered switches

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Year: 2019
Type: article
Abstract: A DNA nanotechnology approach enables label-free and unamplified detection of cellular microRNAs using gel electrophoresis.
Source: Science Advances
DOI: 10.1126/sciadv.aau9443
Authors: Arun Richard Chandrasekaran, Molly MacIsaac, Paromita Dey, Oksana Levchenko, Lifeng Zhou, Madeline Andres, Bijan K. Dey, Ken Halvorsen
Institutions: University at Albany, State University of New York, State University of New York
Language: English

Topic: Advanced biosensing and bioanalysis techniques
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences

Open Access status: gold
Estimated APC paid: $4,500

Funders: American Heart Association, National Institutes of Health, National Cancer Institute, National Institute of General Medical Sciences
Awards: Dysregulation of miR-133a-5p/HMGA2 axis causes skeletal and cardiac muscle degeneration by impairing autophagy in DMD, G3032055725, G3761381504, Single-molecule mechanical detection of protein and microRNA cancer biomarkers, Manipulating nucleic acids: applications in RNA biosensing, single-molecule analysis, and DNA nanotechnology
OpenAlex ID: W2922214118
FWCI: 4.465
Cites: 38
Cited by: 87
Related to: 10
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