Work

Beating the odds: programming proliferation in the mammalian heart

Year: 2018

Type: article

Abstract: The heart is one of the least regenerative organs in the human body; adult cardiac myocytes divide at extremely low frequency. Therefore, meaningful induction of cardiac regeneration requires in-depth understanding of myocyte cell-cycle control. Recent insights into how myocytes can be coaxed into duplicating in vivo might inform emerging therapeutics.

Source: Genome Medicine

DOI: 10.1186/s13073-018-0550-5

Authors: Rajan Jain, Andrey Poleshko, Jonathan A. Epstein

Institution: University of Pennsylvania

Language: English

Topic: Congenital heart defects research

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $5,290