Work

The Role of Advanced Glycation End Products in Diabetic Vascular Complications

Year: 2018

Type: review

Abstract: In cases of chronic hyperglycemia, advanced glycation end-products (AGEs) are actively produced and accumulated in the circulating blood and various tissues. AGEs also accelerate the expression of receptors for AGEs, and they play an important role in the development of diabetic vascular complications through various mechanisms. Active interventions for glucose and related risk factors may help improve the clinical course of patients by reducing AGEs. This review summarizes recent updates on AGEs that have a significant impact on diabetic vascular complications.

Source: Diabetes & Metabolism Journal

DOI: 10.4093/dmj.2017.0105

Authors: Sang Youl Rhee, Young Seol Kim

Institutions: Kyung Hee University, Kyung Hee University Medical Center

Language: English

Topic: Advanced Glycation End Products research

Subfield: Clinical Biochemistry

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $500