Work

PROTAC-induced BTK degradation as a novel therapy for mutated BTK C481S induced ibrutinib-resistant B-cell malignancies

Year: 2018

Type: article

Source: Cell Research

DOI: 10.1038/s41422-018-0055-1

Authors: Yonghui Sun, Xingwang Zhao, Ning Ding, Hongying Gao, Yue Wu, Yiqing Yang, Meng Zhao, Jinseok Hwang, Yuqin Song, Wanli Liu, Yu Rao

Institutions: Tsinghua University, Peking University Cancer Hospital

Language: English

Topic: Protein Degradation and Inhibitors

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Natural Science Foundation of China, Tsinghua University, Ministry of Education, India, Peking University

Awards: G1907363881, G3049762303, G407526976, B细胞淋巴瘤BTK/Stat3基因突变与BTK抑制剂疗效的相关性研究, G801655369, G8215032062

OpenAlex ID: W2806694687

FWCI: 10.04

Cites: 12

Cited by: 285

Related to: 10