Work

Mixed-Effect Time-Varying Network Model and Application in Brain Connectivity Analysis

Year: 2018
Type: preprint
Abstract: Time-varying networks are fast emerging in a wide range of scientific and business applications. Most existing dynamic network models are limited to a single-subject and discrete-time setting. In this article, we propose a mixed-effect network model that characterizes the continuous time-varying behavior of the network at the population level, meanwhile taking into account both the individual subject variability as well as the prior module information. We develop a multistep optimization procedure for a constrained likelihood estimation and derive the associated asymptotic properties. We demonstrate the effectiveness of our method through both simulations and an application to a study of brain development in youth. Supplementary materials for this article are available online.
Language: English
Open Access status: green
OpenAlex ID: W2806865235
Cites: 40
Cited by: 1
Related to: 10