Peptide-Programmable Nanoparticle Superstructures with Tailored Electrocatalytic Activity
Year: 2018
Type: article
Abstract: Biomaterials derived via programmable supramolecular protein assembly provide a viable means of constructing precisely defined structures. Here, we present programmed superstructures of AuPt nanoparticles (NPs) on carbon nanotubes (CNTs) that exhibit distinct electrocatalytic activities with respect to the nanoparticle positions via rationally modulated peptide-mediated assembly. De novo designed peptides assemble into six-helix bundles along the CNT axis to form a suprahelical structure. Surface cysteine residues of the peptides create AuPt-specific nucleation site, which allow for precise positioning of NPs onto helical geometries, as confirmed by 3-D reconstruction using electron tomography. The electrocatalytic model system, i.e., AuPt for oxygen reduction, yields electrochemical response signals that reflect the controlled arrangement of NPs in the intended assemblies. Our design approach can be expanded to versatile fields to build sophisticated functional assemblies.
Source: ACS Nano
Institutions: Sungkyunkwan University, Institute for Basic Science, Chung-Ang University, Korea Basic Science Institute, Pennsylvania State University, University of California, San Francisco, Kyungpook National University, Massachusetts Institute of Technology, Gwangju Institute of Science and Technology
Language: English
Subfield: Biomaterials
Field: Materials Science
Domain: Physical Sciences
Open Access status: green
Funders: National Research Foundation, Ministry of Trade, Industry and Energy, Korea Institute of Science and Technology, National Research Foundation of Korea, Institute for Basic Science, Ministry of Science and ICT, South Korea, Korean National Police Agency, National Institute of General Medical Sciences
OpenAlex ID: W2807430870