Work

Carotid Bodies and the Integrated Cardiorespiratory Response to Hypoxia

Year: 2018

Type: review

Abstract: Advances in our understanding of brain mechanisms for the hypoxic ventilatory response, coordinated changes in blood pressure, and the long-term consequences of chronic intermittent hypoxia as in sleep apnea, such as hypertension and heart failure, are giving impetus to the search for therapies to "erase" dysfunctional memories distributed in the carotid bodies and central nervous system. We review current network models, open questions, sex differences, and implications for translational research.

Source: Physiology

DOI: 10.1152/physiol.00014.2018

Authors: Bruce G. Lindsey, Sarah C. Nuding, Lauren S. Segers, Kendall F. Morris

Institution: University of South Florida

Language: English

Topic: Neuroscience of respiration and sleep

Subfield: Endocrine and Autonomic Systems

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funder: National Institute of Neurological Disorders and Stroke