Work

Differential antibacterial control by neutrophil subsets

Year: 2018

Type: article

Abstract: -banded neutrophils were the only neutrophil subset that adequately contained MRSA. These findings demonstrate a clear neutrophil heterogeneity in their antimicrobial capacity and the appearance of neutrophil subsets with a clear differentiation in functionality during acute inflammation. Furthermore, this study provides an evolutionary basis for the rapid release of banded neutrophils into the circulation during acute inflammation.

Source: Blood Advances

DOI: 10.1182/bloodadvances.2017015578

Authors: Pieter H. C. Leliefeld, Janesh Pillay, Nienke Vrisekoop, Marjolein Heeres, Tamar Tak, Matthijs Kox, Suzan H. M. Rooijakkers, Taco W. Kuijpers, Peter Pickkers, Luke P. H. Leenen, Leo Koenderman

Institutions: University Medical Center Utrecht, Radboud University Nijmegen, Radboud University Medical Center, Amsterdam UMC Location University of Amsterdam, Emma Kinderziekenhuis, University of Amsterdam

Language: English

Topic: Neutrophil, Myeloperoxidase and Oxidative Mechanisms

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,800

Funder: Lung Foundation Netherlands

Awards: G2703256996, G856872339

OpenAlex ID: W2808512787

FWCI: 4.797

Cites: 61

Cited by: 109

Related to: 10