Work

Cannabinoid ligands, receptors and enzymes: Pharmacological tools and therapeutic potential

Year: 2018

Type: article

Abstract: Endocannabinoids have been identified to have roles in numerous physiological and pathological processes. Largely due to the association of the effects of Cannabis administration on mental states, the CNS impact of the endocannabinoid system has been the most intensively studied. Here, we provide a brief summary of the endocannabinoid system, comprising the receptors and the multiple endogenous lipid derivatives which activate them, as well as the enzymes which control the levels of these lipid derivatives. We identify pharmacological tools which may be used to interrogate the endocannabinoid system, as well as current and future options to exploit the system in the clinic.

Source: Brain and Neuroscience Advances

DOI: 10.1177/2398212818783908

Authors: Wafa Hourani, Stephen P. H. Alexander

Institution: University of Nottingham

Language: English

Topic: Cannabis and Cannabinoid Research

Subfield: Pharmacology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,438