Faster and Greener Chemical Reaction Workup Using Silicone Elastomer-Coated Glass Powders
Year: 2018
Type: article
Abstract: We have developed a substantially faster and greener technique for routine chemical reaction workups. We use silicone elastomer-coated glass powder (“FastWoRX”) as an absorbent to extract organic products from a quenched aqueous reaction mixture. After filtration, FastWoRX powder loaded with organic products can serve as a convenient input for flash chromatographic separations. With this technique, tedious and solvent-consuming liquid–liquid extractions are replaced by a simple filtration. Use of FastWoRX reduces solvent use and the E-factor by up to an order of magnitude compared to traditional liquid–liquid extraction-based workup.
Source: ACS Omega
Authors: Zhenyu Shi, Gerald B. Hammond, Bo Xu
Institution: Donghua University
Language: English
Subfield: Physical and Theoretical Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $1,935
OpenAlex ID: W2808985159
