Lighting Up the Mind
Year: 2018
Type: article
Abstract: This visualization shows two-photon imaging of GCamp6f in hippocampal pyramidal neurons as a mouse navigates a virtual reality maze. These techniques give us an indirect measure of activity in neurons or small compartments of neurons in an awake, behaving animal. The hippocampus has been well characterized as playing an essential role in episodic memory. Many hippocampal neurons are “place cells,” cells that fire when an animal is in a specific area of the environment. We can also teleport animals to a new environment and watch as these representations form. Using novel statistical, genetic, and microscopy tools we are examining the mechanisms that underlie this process to better understand memory and navigation.
DOI: 10.21985/n2ct4q
Author: Climer, Jason
Language: English
Topic: Memory and Neural Mechanisms
Subfield: Cognitive Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2809207959