Work

Nanoparticle transport pathways into tumors

Year: 2018

Type: article

Abstract: Two transport pathways (interendothelial and transendothelial routes) have long been proposed for entry of nanoparticles from the blood circulation into solid tumors. We examine and discuss available evidence supporting interendothelial and transendothelial transport processes and suggest new avenues for re-evaluating these pathways. Understanding of integrative mechanisms controlling nanoparticle extravasation into tumors is important for improving engineering and performance of anti-cancer nanopharmaceuticals.

Source: Journal of Nanoparticle Research

DOI: 10.1007/s11051-018-4273-8

Authors: S. M. Moghimi, D. Simberg

Institutions: University of Colorado Anschutz, Newcastle University, University of Colorado Denver

Language: English

Topic: Nanoparticle-Based Drug Delivery

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,890