A novel patient derived orthotopic xenograft model of gastro-esophageal junction cancer: Key platform for translational discoveries
Year: 2018
Type: article
Abstract: Introduction: Mouse models of gastroesophageal junction (GEJ) cancer strive to recapitulate the intratumoral heterogeneity and cellular crosstalk within patient tumors to improve clinical translation. GEJ cancers remain to be a therapeutic challenge due to a lack of reliable mouse model for preclinical drug testing.
Source: Annals of Oncology
Authors: O. Veeranki, Z. Tong, A. Mejia, R. Katkhuda, B. Mino, J. Canales, A. Garcia, W. Lang, R. Bassett, J. Ajani, J. Wu, S. Kopetz, M. Blum, W. Hofstetter, C. Kingsley, W. Norton, D. Maru
Institution: The University of Texas MD Anderson Cancer Center
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $5,080
OpenAlex ID: W2809438108