Work

Diagnostic Accuracy and Utility of FluoroType MTBDR, a New Molecular Assay for Multidrug-Resistant Tuberculosis

Year: 2018

Type: article

Abstract: Most cases of multidrug-resistant (MDR) tuberculosis (TB) are never diagnosed (328,300 of the ∼490,000 cases in 2016 were missed). The Xpert MTB/RIF assay detects resistance only to rifampin, despite ∼20% of rifampin-resistant cases being susceptible to isoniazid (a critical first-line drug).

Source: Journal of Clinical Microbiology

DOI: 10.1128/jcm.00531-18

Authors: Margaretha de Vos, Brigitta Derendinger, Tania Dolby, John Simpson, Paul D. van Helden, John E. Rice, Lawrence J. Wangh, Grant Theron, Robin M. Warren

Institutions: South African Medical Research Council, Stellenbosch University, Brandeis University

Language: English

Topic: Tuberculosis Research and Epidemiology

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Research Foundation, South African Medical Research Council, National Institutes of Health, European and Developing Countries Clinical Trials Partnership

Award: G6671686809

OpenAlex ID: W2810190577

FWCI: 4.147

Cites: 28

Cited by: 51

Related to: 10