Work

Evolution of a chemosensitive core-binding factor AML into an aggressive leukemia with eosinophilic differentiation

Year: 2018

Type: article

Study design: Case Report

Abstract: Key Points Core-binding factor AML can evolve from good-risk disease into aggressive disease through the gain of additional genomic aberrations. In this unique case, an AML patient died of hypereosinophilic syndrome with solid organ infiltration of differentiated eosinophils.

Source: Blood Advances

DOI: 10.1182/bloodadvances.2018016675

Authors: Wenbin Xiao, Mariko Yabe, Michael Offin, Pallavi Khattar, Jeeyeon Baik, Ryan J. Daley, Jeremy J. Pappacena, Mikhail Roshal, Yanming Zhang, Martin S. Tallman, Sheng F. Cai

Institution: Memorial Sloan Kettering Cancer Center

Language: English

Topic: Acute Myeloid Leukemia Research

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,800

Funder: National Cancer Institute

Award: Cancer Center Support Grant

OpenAlex ID: W2810219246

FWCI: 0.179

Cites: 9

Cited by: 3

Related to: 10