Year: 2018
Type: review
Abstract: Noncoding RNAs are emerging as potent and multifunctional regulators in all biological processes. In parallel, a rapidly growing number of studies has unravelled associations between aberrant noncoding RNA expression and human diseases. These associations have been extensively reviewed, often with the focus on a particular microRNA (miRNA) (family) or a selected disease/pathology. In this Mini-Review, we highlight a selection of studies in order to demonstrate the wide-scale involvement of miRNAs and long noncoding RNAs in the pathophysiology of three types of diseases: cancer, cardiovascular and neurological disorders. This research is opening new avenues to novel therapeutic approaches.
Source: FEBS Letters
Authors: Evangelia Lekka, Jonathan Hall
Institutions: ETH Zurich, Institute of Pharmaceutical Sciences
Language: English
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $3,980
Funder: Swiss Cancer Research Foundation
Award: G4597649096
OpenAlex ID: W2810324767