Work

Senomic view of the cell: Senome versus Genome

Year: 2018
Type: review
Abstract: In the legacy of Thomas Henry Huxley, and his 'epigenetic' philosophy of biology, cells are proposed to represent a trinity of three memory-storing media: Senome, Epigenome, and Genome that together comprise a cell-wide informational architecture. Our current preferential focus on the Genome needs to be complemented by a similar focus on the Epigenome and a here proposed Senome, representing the sum of all the sensory experiences of the cognitive cell and its sensing apparatus. Only then will biology be in a position to embrace the whole complexity of the eukaryotic cell, understanding its true nature which allows the communicative assembly of cells in the form of sentient multicellular organisms.
Institution: University of Bonn
Language: English
Open Access status: gold
Estimated APC paid: $1,459
OpenAlex ID: W2848313255
FWCI: 6.842
Cites: 153
Cited by: 70
Related to: 10