Work

Cell-selective expression of a glutamine synthetase fusion gene in embryonic chick retina /

Year: 1995

Type: article

Abstract: CONSTRUCTS demonstrate which sequences of the GS promoter region are responsible for Muller glial cell-specific expression in the retina.The identification of such sequences could, theoretically, have clinical implications in the treatment of ocular diseases.As one may be able to target the production of therapeutic proteins to specific cells of the retina. Chapter I Electroporation as a Tool for the Transfection of Embryonic Chick RetinaWhile a strongly steroid-inducible construct was being sought, these results show no advantage of any particular GS-luciferase fusion construct.

Source: OhioLink ETD Center (Ohio Library and Information Network)

Author: David Andrew Beard

Institution: The Ohio State University

Language: English

Topic: Retinal Development and Disorders

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2849697258

FWCI: 0.123

Cites:

Cited by: 1

Related to: 10