Work

Pharmacokinetics and biodistribution of polymeric micelles containing miRNA and small-molecule drug in orthotopic pancreatic tumor-bearing mice

Year: 2018

Type: article

Abstract: PEG-b-PCC-g-DC-g-TEPA micelles carrying GDC-0449 and let-7b mimic have great potential to improve drug delivery for pancreatic cancer treatment.

Source: Theranostics

DOI: 10.7150/thno.24945

Authors: Virender Kumar, Vaibhav Mundra, Yang Peng, Yingzhe Wang, Chalet Tan, Ram I. Mahato

Institutions: University of Nebraska Medical Center, University of Mississippi

Language: English

Topic: Nanoparticle-Based Drug Delivery

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,671

Funders: University of Nebraska Medical Center, National Institutes of Health, National Institute of General Medical Sciences

Award: Polymeric Nanomedicines of Hedgehog Inhibitor and miRNA for Treating Pancreatic Cancer

OpenAlex ID: W2861934940

FWCI: 1.673

Cites: 39

Cited by: 57

Related to: 10