Work

A strain of Lactobacillus plantarum affects segmented filamentous bacteria in the intestine of immunosuppressed mice

Year: 2008

Type: article

Abstract: Segmented filamentous bacteria (SFB) are present in the gastrointestinal tract of mice from weaning until the maturation of the immune system. Probiotic bacteria also have an effect on host immunity. To study the relationships established between these bacteria, samples from a mouse model fed with Lactobacillus plantarum under different immunological conditions were analysed. SFB populations were measured by a newly designed group-specific quantitative PCR assay. The results confirmed the presence of the probiotic in the intestine and an expansion of SFB in the ileum of immunocompromised mice, which was abolished upon administration of L. plantarum, an effect not described to date.

Source: FEMS Microbiology Ecology

DOI: 10.1111/j.1574-6941.2007.00411.x

Authors: Susana Fuentes, Markus Egert, Maria Jimenez-Valera, Mercedes Monteoliva-Sanchez, Alfonso Ruiz-Bravo, Hauke Smidt

Institutions: Universidad de Granada, Wageningen University & Research

Language: English

Topic: Probiotics and Fermented Foods

Subfield: Food Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: European Commission, Universidad de Granada, European Regional Development Fund