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Meganuclease targeting of PCSK9 in macaque liver leads to stable reduction in serum cholesterol

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Year: 2018
Type: article
Source: Nature Biotechnology
DOI: 10.1038/nbt.4182
Authors: Lili Wang, Jeff Smith, Camilo Breton, Peter Clark, Jia Zhang, Lei Ying, Yan Che, Janel Lape, Peter Bell, Roberto Calcedo, Elizabeth L Buza, Alexei Saveliev, Victor V Bartsevich, Zhenning He, John White, Mingyao Li, Derek Jantz, James M Wilson
Institutions: University of Pennsylvania, Precision BioSciences (United States)
Language: English

Topic: Virus-based gene therapy research
Subfield: Genetics
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funder: University of Pennsylvania Health System
OpenAlex ID: W2867029183
FWCI: 7.625
Cites: 61
Cited by: 120
Related to: 10
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