Work

Small-Molecule G Protein–Coupled Receptor Kinase Inhibitors Attenuate G Protein–Coupled Receptor Kinase 2–Mediated Desensitization of Vasoconstrictor-Induced Arterial Contractions

Year: 2018

Type: article

Source: Molecular Pharmacology

DOI: 10.1124/mol.118.112524

Authors: Richard D. Rainbow, Sean Brennan, Robert Jackson, Alison J. Beech, Amal Bengreed, Helen V. Waldschmidt, John J.G. Tesmer, R.A. John Challiss, Jonathon M. Willets

Institutions: University of Leicester, Purdue University West Lafayette, University of Michigan, Glenfield Hospital

Language: English

Topic: Receptor Mechanisms and Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: British Heart Foundation, University of Leicester, National Institutes of Health, National Heart, Lung, and Blood Institute

Awards: Structure and Function of the LPLA2/LCAT Acyltransferase Family, G1468576729, Understanding mechanisms of cardioprotection: the overlooked role of Kir6.1 in cardiac muscle, G protein-coupled receptor kinase- and arrestin-dependent mechanisms controlling cell migratory and proliferative responses of arterial smooth muscle, G4026372967, Investigating the causes and consequences of G-protein-coupled receptor kinase (GRK) and arrestin up-regulation in vascular smooth muscle in hypertension, G4675322906, G750832604, Structure, function, and inhibition of G protein-coupled receptor kinases

OpenAlex ID: W2872971550

FWCI: 0.444

Cites: 43

Cited by: 18

Related to: 10