Work

Yeast and Filaments Have Specialized, Independent Activities in a Zebrafish Model of Candida albicans Infection

Year: 2018

Type: article

Abstract: Candida albicans dimorphism is a crucial virulence factor during invasive candidiasis infections, which claim the lives of nearly one-half of those afflicted. It has long been believed that filaments drive tissue invasion and yeast mediates bloodstream dissemination, but observation of these activities during infection has been prevented by technical limitations.

Source: Infection and Immunity

DOI: 10.1128/iai.00415-18

Authors: Brittany G. Seman, Jessica L. Moore, Allison K. Scherer, Bailey A. Blair, Sony Manandhar, Joshua M. Jones, Robert T. Wheeler

Institution: University of Maine

Language: English

Topic: Antifungal resistance and susceptibility

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: U.S. Department of Agriculture, Burroughs Wellcome Fund, National Institutes of Health, National Institute of Allergy and Infectious Diseases

Awards: G1426576235, Intravital study of innate immunity to mucosal candidiasis, Genetics and visualization of innate host response to C. albicans infection in vi, G7428350954

OpenAlex ID: W2883421083

FWCI: 2.749

Cites: 83

Cited by: 44

Related to: 10