Work

Visible-Light Photocatalytic Difluoroalkylation-Induced 1, 2-Heteroarene Migration of Allylic Alcohols in Batch and Flow

Year: 2018

Type: article

Abstract: -rich heterocycles is reported. The method comprises a photocatalytic difluoroalkylation-induced 1,2-heteroarene migration of allylic alcohols. Here we describe for the first time the benefits of using flow to facilitate such migration reactions, including shorter reaction times, higher selectivities, and opportunities to scale the chemistry.

Source: The Journal of Organic Chemistry

DOI: 10.1021/acs.joc.8b01624

Authors: Xiao-Jing Wei, Timothy Noël

Institution: Eindhoven University of Technology

Language: English

Topic: Radical Photochemical Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $4,500

Funders: European Commission, Nederlandse Organisatie voor Wetenschappelijk Onderzoek